Cocaine overtakes heroin as leading cause of drug deaths in England and Wales

The number of deaths from cocaine use in England and Wales has nearly quadrupled in a decade, overtaking those attributed to heroin for the first time. Cocaine was linked to more than one in five drug poisoning deaths registered in 2025, more than any other single substance, with charities blaming its increased purity and availability. Meanwhile a record 115 ketamine-linked deaths were registered, almost twice as many as in 2024, according to Office for National Statistics data , external .

The overall rate of drug deaths fell for the first time since 2012. But experts pointed out regional inequality was growing, with the rate of such deaths more than twice as high in the North East as in London. There were 5,519 drug poisoning deaths registered in 2025 in England and Wales, the equivalent of 92.4 deaths per million people.

Of these, cocaine was mentioned in 1,233 cases - slightly fewer than the previous year but higher than the 1,210 deaths linked to heroin or morphine, which also marked a fall from the previous year's level.